Wearable computing systems and applications have attracted interest from a broad range of interdisciplinary researchers and practitioners for decades. The rapid proliferation of wearable computing—from smartphones, smartwatches, on-skin interfaces, implantables, and to head-mounted immersive platforms—has been driven by technological advances and increasing consumer acceptance. However, despite their growing maturity, several key challenges continue to hinder their adoption in long-term, real-world deployments. These include, but are not limited to, novel hardware and platform design, security and privacy concerns, effective integration of advanced machine learning for on-device intelligence and context awareness, system energy and computational efficiency, and improving user adherence and overall experience.